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ALPINION MEDICAL SYSTEMS

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Therapeutic
Ultrasound

VIFU 2000
Key FeaturesMove to Top

• Ultrasound guided non-invasive procedure.

• Real-time monitoring

• Precise targeting for accurate treatment
(converged by ALPINION’s proprietary HIFU and imaging transducer technologies)

• Wet or Dry platform to accommodate various applications
(easy and fast switching between Wet and Dry platform depending on types of study)

• Turnkey bench-top system ideally designed for laboratory.

Research Case

PASSIVE CAVITATION DETECTION DURING PULSED HIFU EXPOSURES OF
EX VIVO TISSUES AND IN VIVO MOUSE PANCREATIC TUMORS

TONG LI, HONG CHEN, TATIANA KHOKHLOVA, YAK-NAMWANG, WAYNE KREIDER,
XUEMEIHE, and JOO HA HWANG (Team of University of Washington)

PULSED FOCUSED ULTRASOUND PRETREATMENT IMPROVES MESENCHYMAL STROMAL CELL EFFICACY
IN PREVENTING AND RESCUING ESTABLISHED ACUTE KIDNEY INJURY IN MICE

SCOTT R. BURKS, BEN A. NGUYEN, PAMELA A. TEBEBI, SAEJEONG J. KIM,
MICHELE N. BRESLER, ALI ZIADLOO, JONATHAN M. STREET, PETER S. T. YUEN, ROBERT A. STAR, JOSEPH A. FRANK

PULSED HIGH-INTENSITY FOCUSED ULTRASOUND ENHANCES DELIVERY OF DOXORUBICIN
IN A PRECLINICAL MODEL OF PANCREATIC CANCER

TONG LI, YAK-NAM WANG, TATIANA D. KHOKHLOVA, SAMANTHA D'ANDREA,
FRANK STARR, HONG CHEN, JEANNINE S. MCCUNE, LINDA J. RISLER, AFSHIN MASHADI-HOSSEIN, JOO HA HWANG

ApplicationsMove to Top
Solid tumor ablation In-vivo / Ex-vivo study Enhanced drug delivery study
Cavitation effect study Opening the blood brain barrier
(BBB)
Histotripsy Animal treatment
Target UsesMove to Top

• VIFU 2000 WET Size : Up to 6.3” x 2.8” (Length x Height, tail excluded) • VIFU 2000 DRY Size : Up to 25” x 7” x 9” (Length x Height x Width, tail excluded) / Weight : Up to 50 lbs

Key End UsersMove to Top

• University laboratory

• Research institutes / hospitals

• Cancer research laboratory

• Government laboratory

• Pharmaceutical companies

• Bio-medical companies

• Veterinary center

• Animal hospitals